Dr. Anita Mahapatra

Asst. Professor

Department of Natural Products
National Institute of Pharmaceutical Education and Research (NIPER)
Tele : +91 79 27439375
Ext : 302
E.mail : anita@nipergn.ac.in,

RESEARCH Interest :

Target oriented and lead based design and development of New Chemical Entities (NCEs) of natural scaffolds against Diabetes, TB and Cancer, Discovery of new bioactive leads from natural sources for cancer and neuroprotection, Development of National repository of secondary metabolites

EDUCATION :

Post Doctoral Fellow – University of Pretoria, Pretoria, South Africa - 2005

Ph. D. – (Organic Chemistry) Utkal University, Bhubaneswar, Odisha - 2001

B. Ed. – (Science & Maths.) Berhampur University, Berhampur, Odisha - 1991

M. Sc. – (Organic Chemistry) Berhampur University, Berhampur, Odisha - 1989

B. Sc. – (Chemistry Hons.) Berhampur University, Berhampur, Odisha - 1987

EXPERIENCE
  • Asst. Professor - Present (Sept-2008) : NIPER-Gandhinagar, C/o B. V. Patel PERD Centre, S G Highway, Thaletj, Ahmedabad
  • Scientist Fellow (June-2006 to Sept-2008) : CSIR, Institute of Minerals and Material Technology (formerly RRL), Bhubaneswar, Odisha
  • Post Doctoral Fellow (Aug-2004 to July-2005) : University of Pretoria, Pretoria, South Africa
  • Research Associate (June-2003 to May-2006) : CSIR, Regional Research Laboratory, Bhubaneswar, Odisha
  • Senior Project Fellow (Nov-1997 to May-2003) : Regional Research Laboratory, Bhubaneswar, Odisha
  • Senior Project Assistant (Feb-1994 to Oct-1997) : Regional Research Laboratory, Bhubaneswar, Odisha
Awards and Memberships :
  • Best Poster Award at National conference on Herbal drugs: opportunities and challenges, Ahmedabad November (2014)
  • Prof. A.R. Rao Memorial Best Young Researcher Award at International Conference on "Recent Advances in Cancer Research - Therapeutics to Chemoprevention, Ahmedabad February (2012).
  • Dr. P.D. Sethi Award for the Best Research Paper on "Application of TLC/ HPTLC in Pharma, Herbal and other Analysis" (2008)
  • DST Women Scientist Award (Dept. Science & Technology, 2003)
  • National Scholarship for Merit, after graduation for the year 1987-89
  • Membership : Life member, Odisha Chemical Society
Publications :
  • Anita Mahapatra*, P. Shah, M. Jivrajani and M. Nivsarkar, Synthesis and blastocyst implantation inhibition potential of lupeol derivatives in female mice, Records of Natural Products 9 (4), 561-566. (2015)
  • Anita Mahapatra*, N. Chauhan, D. R. Patel, N. P. Kalia, V. S. Rajput and I. A. Khan, Synthesis and anti-tubercular activity of oleanolic acid analogues, Pharmaceutical Chemistry Journal, 48(1), 39-43. (2014) DOI. 10.1007/s11094-014-1042-6
  • Anita Mahapatra*, V. Maheswari, N. P. Kalia, V. S. Rajput and I. A. Khan, Synthesis and anti-tubercular activity of berberine derivatives, Chemistry of Natural Compounds, 50(2), 321-325. (2014) DOI. 10.1007/s10600-014-0942-8
  • N. Kishore, B. Binneman, Anita Mahapatra, M. van de Venter, D. du Plessis-Stoman, G. Boukes, P. Houghton, J.J.M. Meyer, N. Lall, Cytotoxicity of synthesized 1,4-naphthoquinone analogues on selected human cancer cell lines, Bioorganic Medicinal Chemistry, 22(17), 5013-5019. (2014) DOI. 10.1016/j.bmc. 2014.06.013
  • U. V. Mallavadhani, Anita Mahapatra, B. Pattnaik, N. Suri, A. K. Saxena, Synthesis and anti-cancer activity of some novel C-17 analogs of ursolic and oleanolic acids, Medicinal Chemistry Research. 22(3), 1263-1269. (2013) DOI. 10.1007/s00044-012-0106-y
  • U. V. Mallavadhani, Anita Mahapatra and S. Mohapatra, An efficient chemical method for separation of corsolic acid from its isomeric maslinic acid, Natural Products Research, 20(10), 946-952. (2006) DOI. 10.1080/14786410500463254
  • Anita Mahapatra, S. P. N. Mativandlela, B. Binneman, P. B. Fourie, Chris J. Hamilton, J. J .M. Meyer, F van der Kooy, P. Houghton and N. Lall, Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase, Bioorganic Medicinal Chemistry, 15(24), 7638-7646. (2007) DOI. 10.1016/j.bmc.2007.08.064
  • U. V. Mallavadhani, K. Narasimhan, A.V.S. Sudhakar, Anita Mahapatra, W. Li and R.B. Van Breemen, Three new pentacyclic triterpenes and some flavonoids from the fruits of an Indian ayurvedic plant Dendrophthoe falcata and their estrogen receptor binding activity, Chemical and Pharmaceutical Bulletin, 54(5),740-744. (2006) DOI. 10.1248/cpb.54.740
  • U. V. Mallavadhani, K.V.S. Satyanarayana, Anita Mahapatra, and A.V.S. Sudhakar, A new tetracyclic triterpene from the latex of Euphorbia nerifolia, Natural Products Research, 18(1), 33-37. (2004) DOI.10.1080/1057563031000122068
  • U. V. Mallavadhani, Anita Mahapatra, S. Sabitha Raja and C. Manjula, Antifeedant activity of some pentacyclic triterpene acids and their fatty ester analogues, Journal of Agricultural and Food Chemistry, 51(7), 1952-1955. (2003) DOI.10.1021/jf020691d
  • Anita Mahapatra, Chemical Screening of Diospyros melanoxylon leaves : Search for Alternative uses, Ph.D. thesis submitted to Utkal University (2000)
PATENTS : 04
Presentations : 25
MONOGRAPHS : 30
Projects : 11
MS Dissertation : 26